Resumo

LIU, F et al. Ex vivo antioxidation activity of polysaccharides from the red alga Porphyra yezoensis. Cienc. mar [online]. 2008, vol.34, n.2, pp.253-261. ISSN 0185-3880.

The ex vivo antioxidation activity of polysaccharide extracted from the red seaweed Porphyra yezoensis was studied by systematically measuring and analyzing the scavenging efficiencies on the free radicals O^-₂·, -OH and DPPH, and the inhibitory effects on the hemolysis in mouse erythrocytes induced by H₂O₂ and on lipid peroxidation in mouse liver homogenates. The results show that Porphyra polysaccharide, in the experimental concentration range, possessed antioxidation activity. The scavenging efficiency for O^-₂· was found to be remarkably high and the maximum scavenging rate was 82.77%. The scavenging efficiency for ·OH was even higher than for O^-₂·, with a maximum removing rate of 85.63%, whereas for DPPH it was 13.97%. The inhibitory effects on mouse erythrocyte hemolysis and malondialdehyde formation in mouse liver were significant, with maximum inhibition rates of 82.90% and 58.48%, respectively. The combined data indicate that the polysaccharide extracted from Porphyra has strong antioxidation activity.

Palavras-chave : Porphyra yezoensis; polysaccharide; antioxidation; free radical.

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