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Salud Pública de México

Print version ISSN 0036-3634


MIRANDA-NOVALES, María Guadalupe  and  UNCAR NETWORK et al. Antimicrobial resistance and antibiotic consumption in Mexican hospitals. Salud pública Méx [online]. 2020, vol.62, n.1, pp.42-49.  Epub Feb 28, 2022. ISSN 0036-3634.


To establish the current situation of antimicrobial resistance and antibiotic consumption in Mexican hospitals.

Materials and methods:

Antimicrobial susceptibility data from blood and urine isolates were collected. Defined daily dose (DDD) of antibiotic consumption/100 occupied beds (OBD) was calculated.


Study period: 2016 and 2017. Of 4 382 blood isolates, E. coli and K. pneumoniae were most frequently reported, with antimicrobial resistance >30% for most drugs tested, only for carbapenems and amikacin resistance were <20%. A. baumannii had antimicrobial resistance >20% to all drugs. Resistance to oxacillin in S. aureus was 20%. From 12 151 urine isolates, 90% corresponded to E. coli; resistance to ciprofloxacin, cephalosporins and trimethoprim/sulfamethoxazole was >50%, with good susceptibility to nitrofurantoin, amikacin and carbapenems. Global median antimicrobial consumption was 57.2 DDD/100 OB.


This report shows a high antimicrobial resistance level in Gram-negative bacilli and provides an insight into the seriousness of the problem of antibiotic consumption.

Keywords : anti-bacterial agents; drug resistance, microbial; drug utilization.

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