SciELO - Scientific Electronic Library Online

 
vol.52 número6Estimación de costos de la atención de pacientes con cirrosis hepática en el Instituto Mexicano del Seguro Social índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Salud Pública de México

versión impresa ISSN 0036-3634

Resumen

HERNANDEZ-SUAREZ, Gustavo; ORTIZ, Natasha; GONZALEZ, Mauricio  y  MUNOZ, Nubia. Short-term risk of cervical intraepithelial neoplasia grades 2 and 3 for women with normal cytology and human papillomavirus infection. Salud pública Méx [online]. 2010, vol.52, n.6, pp. 486-492. ISSN 0036-3634.

OBJECTIVE. To assess the risk of cervical intraepithelial neoplasia grades 2, 3 or higher (CIN 2/3+) for women with normal cytology and concurrent high-risk human papillomavirus infection (HR-HPV). MATERIAL AND METHODS. We examined 2 200 women every 6 months for an average of 9 years. Cervical smears and samples for HPV DNA were obtained at each visit. Absolute risk of subsequent CIN2/CIN3+ was estimated using the Kaplan-Meier method. RESULTS. The absolute risk of CIN2/CIN3+ among HR-HPV-positive women with normal Pap smear results was 1.06% (95%CI, 0.57-2.20), 5 times higher the risk among all women with normal Pap smears (0.20%; 95%CI, 0.12-0.32) but 7 times lower than that for women with HR-HPV infection and LSIL (7.24%; 95%CI, 3.78-15.2). CONCLUSION. Short-term absolute risk of CIN2/3+ after a normal Pap smear with concurrent HR-HPV infection is low (~1%), suggesting that the HR-HPV test has limited utility in short-term clinical decision-making for women with normal cytology.

Palabras llave : cervical intraepithelial neoplasia; human papilloma virus; risk assessment; Colombia.

        · resumen en Español     · texto en Inglés     · pdf en Inglés