Resumo

FLORES, Mario et al. C-reactive protein concentrations in Mexican men and women: high prevalence of a cardiovascular risk factor. Salud pública Méx [online]. 2007, vol.49, suppl.3, pp.s348-s360. ISSN 0036-3634.

OBJECTIVE: To examine the distribution and correlates of C-reactive protein (CRP) concentrations in Mexican adults. MATERIAL AND METHODS: Data was analyzed from 2 194 Mexican adults who participated in the 2000 National Health Survey (ENSA-2000). CRP concentrations were measured with a high-sensitivity assay. Information on sociodemographic characteristics, chronic disease and habits was obtained. Fasting blood glucose, blood pressure, weight, height and waist circumference were measured. RESULTS: A total of 730 men and 1 464 non-pregnant women were studied. Mean age was 38.3±15.2 years. CRP concentrations ranged from 0.19 to 255 mg/L (median: 2.26; interquartile range (FIR): 0.96, 5.83 mg/L). CRP concentrations were higher in women (median: 2.86; IR: 1.11, 6.68 mg/L) than men (median: 1.63; IR: 0.8, 3.87 mg/L; p<0.001). Thirty-one percent of individuals (35.1% women, 23.3% men) had CRP concentrations >3.0-10 mg/L. Multivariate probit regression analysis showed that age, BMI, waist circumference, diabetes, microalbuminuria and use of oral contraceptives were positively associated with CRP concentrations >1 mg/L. Male gender and moderate alcohol consumption were negatively associated with CRP concentrations >3 mg/L (p<0.05). CONCLUSION: There is a high prevalence of CRP concentrations in the range of >3.0-10 mg/l in Mexican adults, indicating a considerable proportion of individuals at risk for cardiovascular disease, independent of other risk factors.

Palavras-chave : C-reactive protein; CRP; cardiovascular disease; obesity; national surveys; Mexico.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )