Abstract

RAMIREZ-LOPEZ, Guadalupe et al. Triglycerides and high-density lipoprotein cholesterol are associated with insulinemia in adolescents. Salud pública Méx [online]. 2006, vol.48, n.4, pp.293-299. ISSN 0036-3634.

OBJECTIVE: The aim of this study was to evaluate the association between lipids and insulin concentration in adolescents. MATERIAL AND METHODS: A cross-sectional study of 350 adolescents aged 14-19 years old from a public high school in Guadalajara, in the state of Jalisco, Mexico, was conducted. Fasting insulin concentration was determined using microparticle enzyme immunoassay; total cholesterol and triglycerides were detected by standard enzymatic procedures; and low- and high-density lipoproteins were found using standard precipitation methods. Statistical analysis included linear multivariate regression. RESULTS: Serum triglycerides were associated positively with insulin fasting (b= 0.003, p= 0.0001) and high-density lipoprotein cholesterol was negatively associated with insulin fasting in male adolescents 18-19 years old (b= -0.03, p= 0.012). CONCLUSIONS: The relationships between triglycerides and insulin and between high-density lipoprotein cholesterol and insulin are already present in adolescence.

Keywords : triglycerides; high-density lipoprotein cholesterol; lipids; insulin; obesity; adolescents; Mexico.

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