SciELO - Scientific Electronic Library Online

 
vol.57 número3¿Es bacteriostático el jugo de arándano?Mecanismos moleculares de acción de los ácidos grasos poliinsaturados y sus beneficios en la salud índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

  • No hay artículos similaresSimilares en SciELO

Compartir


Revista de investigación clínica

versión impresa ISSN 0034-8376

Resumen

MENDEZ, Isabel; CARINO, Cecilia  y  DIAZ, Lorenza. Prolactin in the immune system: synthesis and biological effects. Rev. invest. clín. [online]. 2005, vol.57, n.3, pp.447-456. ISSN 0034-8376.

Prolactin (PRL) Is a 23 κDa protein hormone that is produced and secreted by the pituitary lactotrophs. Although PRL was initially regarded as an exclusive pituitary hormone, many nonpituitary tissues were later found to contain and produce this hormone. The most established extrapituitary sites that produce PRL are the decidua, the immune system, brain and endometrium. In the immune system, PRL acts as a cytokine where it plays an important role in human immune responses, including in autoimmune diseases. Here, we will discuss the regulation of PRL gene expression in human lymphocytes and review the functions of PRL made by the immune cells, including its involvement in autoimmunity.

Palabras llave : Prolactin; Cytokine; Lymphocytes; Gene expression; Autoimmunity.

        · resumen en Español     · texto en Español     · Español ( pdf )

 

Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons