Servicios Personalizados
Revista
Articulo
Indicadores
- Citado por SciELO
- Accesos
Links relacionados
- Similares en SciELO
Compartir
Revista de la Facultad de Medicina (México)
versión On-line ISSN 2448-4865versión impresa ISSN 0026-1742
Resumen
VILLEGAS-SERRANO, E. Yazmín; AGUILAR-VEGA, Laura; PEREZ-ARMENDARIZ, E. Martha y ZURABIAN, Rimma. Maturative lineages of cells that regenerate the liver. Rev. Fac. Med. (Méx.) [online]. 2017, vol.60, n.2, pp.5-10. ISSN 2448-4865.
Different cellular lineages participate in liver regeneration. Quiescent hepatocytes may respond to a mild liver injury with moderate cell division. Meanwhile, stem and progenitor cells are responsible for the large restitution of a severe damaged organ. Eight matu rational lineages are in the liver, each one with a different maturity grade. Four subpopulations out of eight express stem or progenitor cell markers are found within intrahepatic niches such as the canals of Hering and the portal vein. Each structure is able to continue its differentiation if a stimuli is received. Recently, a new extra-hepatic stem niche with a heterogeneous cellular composition was found between the large biliary ducts and the pancreas. Stem or progenitor cells contained in these compartments express early stem markers and are considered as a precursor of hepatic stem cells.
Palabras llave : Liver; bile ducts; stem cells; regeneration.