Abstract

VALENCIA HUERTA, Octavio et al. Unusual location of multiple myeloma lytic lesions with magnetic resonance imaging. Report of two cases. Rev. Fac. Med. (Méx.) [online]. 2015, vol.58, n.1, pp.40-47. ISSN 2448-4865.

Multiple myeloma (MM) is an hematologic malignancy characterized by the proliferation of malignant monoclonal plasma cells in the bone marrow. The diagnostic test for MM is a bone marrow aspirate or biopsy to define the amount of atypical plasma cells and it is the basis of the diagnostic classification system of the International Working Group Myeloma.

MM lesions are lytic bone tissue and are most frequently located in the spine, pelvis, skull and ribs. Bone lesions predominate in these regions of the skeleton and proximal extremities but may occur to a lesser extent on elbows, knees and scapula.

In imaging studies plain radiography remains the primary diagnostic study in detecting destructive bone changes multiple myeloma, however the MRI study is the study of choice because the sensitivity and specificity for the diagnosis of this disease.

Objectives: Report two cases with multiple myeloma infiltration in unusual regions.

Keywords : unusual lesions; multiple myeloma; MRI.

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