Abstract

ALANIZ SANCHEZ, Alfredo; ORTUNO LOPEZ, Mayra; CRUZ GONZALEZ, Marisol  and  ALANIZ GARCIA, Tania Lizeth. Low-Grade Squamous Intraepithelial Lesion and its cyto-colpo-histologic correlation. Rev. Fac. Med. (Méx.) [online]. 2011, vol.54, n.6, pp.13-17. ISSN 2448-4865.

Introduction: The detection of the early lesions precursors of uterine cervix carcinoma is carried out based on the interpretation of Papanicolaou smear. Objective: To determine the correlation that exists betweeen cervical cytology compared with the diagnosis by either colposcopy or histology in the Low-Grade Squamous Intraepithelial Lesion (LSIL). Material and methods: 100 patients with cytology compatible with LSIL are practiced colposcopy taking directed biopsy for histopathologic study. Results: Average age: 37; Average onset of sexually active life: 19.25 years old; number of sexual partners: 2.57; condom use in 0.3%. 45% of the patients were smokers. Diagnosis by cytology: LSIL in 77 (77%) of the patients, inflammatory process 20 (20%), and HSIL 3 (3%). Sensibility: 88.23%; specificity 42.85%; positive predictive value (PPV): 94.93%, and negative predictive value (NPV): 23.07%. LSIL diagnosis by cytology: 85 patients (85%); inflammatory process: 13 (13%); HSIL: 2 (2%); Sensibility: 79.12%; specificity: 28.57%; PPV: 93.50%; NPV: 9.52%. The colposcopy with Reid index and diagnosis of LSIL: 92 (92%) patients; inflammatory process: 6 (6%); HSIL: 2 (2%); Sensibility: 93.47%; Specificity: 33.33%; PPV: 95.55%; NPV: 25%. The gold standard was histopathology: 100% with a diagnosis of LSIL. Conclusion: Before an abnormal cytology, colposcopy with directed biopsy should be performed for a more accurate diagnosis. Cytology will remain a good screening test due to its usefulness to detect early cervical lesions.

Keywords : Cervical cytology; Low-Grade Squamous Intraepithelial Lesion.

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