Servicios Personalizados
Revista
Articulo
Indicadores
- Citado por SciELO
- Accesos
Links relacionados
- Similares en SciELO
Compartir
Gaceta médica de México
versión On-line ISSN 2696-1288versión impresa ISSN 0016-3813
Resumen
DELGADO-DE LA MORA, Jesús et al. Clinical features of patients with Rocky Mountain spotted fever, dengue and chikungunya infection. Gac. Méd. Méx [online]. 2021, vol.157, n.1, pp.61-66. Epub 18-Jun-2021. ISSN 2696-1288. https://doi.org/10.24875/gmm.20000105.
Introduction:
Clinical distinction between arbovirus infections and those caused by rickettsia is crucial to initiate appropriate medical treatment.
Objective:
To compare the differences between Rocky Mountain spotted fever (RMSF) and other vector-borne diseases (dengue and chikungunya) with similar clinical presentation, and to identify data that could aid rapid diagnosis of these diseases.
Methods:
Sociodemographic, clinical and laboratory data of 399 patients from five hospitals and clinics of Sonora, Mexico, with laboratory-confirmed diagnosis of RMSF, dengue, or chikungunya between 2004 and 2016 were evaluated.
Results:
The RMSF group had the highest lethality (49/63 deaths, 77.8 %), followed by the chikungunya group (3/161, 1.9 %) and the dengue group (3/161, 1.9 %). Clinical differences included the presence of rash, edema, and pruritus; in addition, differences in multiple biomarkers such as platelets, hemoglobin, indirect bilirubin, and serum sodium levels were documented.
Conclusion:
Rash on the palms and soles, edema and absence of pruritus, together with high levels of direct bilirubin and severe thrombocytopenia could be useful indicators to differentiate patients at RMSF advanced stages from those with dengue and chikungunya.
Palabras llave : Rocky Mountain spotted fever; Dengue; Chikungunya; Mexico.