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Gaceta médica de México
versão On-line ISSN 2696-1288versão impressa ISSN 0016-3813
Resumo
RODRIGUEZ-SALGADO, Pamela e GARCIA-ROMERO, María Teresa. Morphea: a practical review of its diagnosis, classification and treatment. Gac. Méd. Méx [online]. 2019, vol.155, n.5, pp.483-491. Epub 01-Jul-2021. ISSN 2696-1288. https://doi.org/10.24875/gmm.m20000336.
Morphea, or localized scleroderma, is a rare disease of the connective tissue that manifests itself with localized sclerosis of the skin and, in some cases, with extracutaneous manifestations. Its etiology is not fully understood, but it is believed that there is genetic predisposition, in addition to environmental triggering factors. Classification of the disease is not simple due to its multiple presentations; however, it is useful in order to define the treatment, which should be individualized and started early to avoid cosmetic and functional complications. In this review, we summarize the most important practical aspects of the classification, diagnostic methods and evaluation of morphea activity, as well as available therapeutic options, with an emphasis on existing clinical evidence regarding their efficacy and safety.
Palavras-chave : Morphea; Localized scleroderma; Lichen sclerosus et atrophicus.