Abstract

CANEDO-PATZI, Ana Marcela; DE LEON-BOJORGE, Beatriz  and  ORTIZ-HIDALGO, Carlos. Adenomatoid tumor of the genital tract. Clinical, pathological and immunohistochemical study in 9 cases. Gac. Méd. Méx [online]. 2006, vol.142, n.1, pp.59-66. ISSN 2696-1288.

Objetive: Describe the histological and immunohistochemical features of nine genital tract adenomatoid tumors . Material and methods: Nine cases of adenomatoid tumors were collected from the files of the Pathology department at a private hospital (ABC Hospital). Tumors were studied from a histological and inmunohistochemical perspective. Results: Eight women and one man were studied. Age range was 28-54 yrs. Tumors were located in the uterus (seven), fallopian tube (one) and epididymis (one). Tumor size ranged from 0.4 to 5.8 cm. We observed three histological patterns: adenoid, angiomatoid and solid. Arrangement of the neoplastic tubules around fascicles of smooth muscle; angiomatoid pattern with a peripheral location, and solid and adenoid patterns with a central location in the tumor were some of the observed histological features. Immunohistochemically all tumors exhibited strong and diffuse positivity for calretinin and AE1/AE3. Thrombomodulin was positive in all tumors (focal and weak in angiomatoid pattern and diffuse and strong in adenoid and solid patterns). The CK5/6 antibody was positive in seven tumors (diffuse in three and focal in four). Two tumors were negative for this marker. All tumors were negative for CD31. Conclusions: The immunophenotype of the adenomatoid tumors in our series confirms their mesothelial origin.

Keywords : Adenomatoid tumor; mesothelial histogenesis; immunohistochemistry.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )