Gaceta médica de México
versión impresa ISSN 0016-3813
SADA-OVALLE, Isabel et al. CD1 pathway and NK T Cell activation to glycolipid antigens from Mycobacterium. Gac. Méd. Méx [online]. 2005, vol.141, n.1, pp. 35-41. ISSN 0016-3813.
The aim of this review is to analyze the current state of our knowledge about cell surface molecules involved in glycolipid antigen presentation, named CD1 family. These proteins constitute a third class of antigen-presenting molecules. CD 1 molecules develop diverse important immune functions in host defenses against microbial infections. In recent years these proteins have been involved in the generation of cell-mediated immune response against Mycobacterium tuberculosis. Here, we analyze relevant roles of CD1 proteins and glycolipid antigen-specific T cells.
Palabras llave : CD1; CD8+ T cells; NK T cells; Mycobacterium tuberculosis.