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Journal of the Mexican Chemical Society
versión impresa ISSN 1870-249X
J. Mex. Chem. Soc vol.49 no.2 Ciudad de México 2005
Short Report
Short Synthesis of a New Cyclopentene-1,3-dione Derivative Isolated from Piper carniconnectivum
Luiz C. Dias*, Simone B. Shimokomaki and Robson T. Shiota
Instituto de Química, Universidade Estadual de Campinas, CP 6154, 13083-970 Campinas - SP, Brazil. * e-mail: ldias@iqm.unicamp.br
Received: September 20, 2004
Published on the web: March 30, 2005
Abstract
The total synthesis of cyclopentene-1,3-dione (1), a new natural cyclopentenedione derivative isolated from the roots of Piper carniconnectivum, is described in 8 steps and 11% overall yield from 2-acetylfuran, giving a 57:43 mixture of the two possible geometric isomers 1a and 1b.
Keywords: aldol reaction, allylic alcohol oxidation, cyclopentenedione derivative, Piper carniconnectivum
Resumo
А síntese total da ciclopentenodiona (1), isolada das raízes de Piper carniconnectivum, é descrita em 8 etapas e 11% de rendimento global a partir do 2-acetilfurano, fornecendo uma mistura 57:43 dos dois possíveis isômeros geométricos 1a e 1b.
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References
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Notes
Dedicated to Prof. Raimundo Braz-Filho for his outstanding contributions to the field of Organic Chemistry in Brazil.