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Revista mexicana de física
versão impressa ISSN 0035-001X
Resumo
BETANCOURT-PADRON, P. J.; GARCIA-MEDINA, K.; MANSILLA, R. e NIETO-VILLAR, J. M.. Phase transition in tumor growth VIII: The spatiotemporal avascular evolution. Rev. mex. fis. [online]. 2020, vol.66, n.6, pp.856-862. Epub 31-Jan-2022. ISSN 0035-001X. https://doi.org/10.31349/revmexfis.66.856.
A 2D cellular automata model, which allows a better understanding of the morphogenesis of the avascular tumor pattern formation, is presented. Using thermodynamics formalism of irreversible processes and results of complex systems theory, we propose features that establish, in a quantitative way, the degree of aggressiveness and the malignancy of tumor patterns, such as a fractal dimension and the entropy production rate.
Palavras-chave : Biological phase transition; cellular automata; avascular tumor growth; entropy production rate; fractal dimension.