SciELO - Scientific Electronic Library Online

 
vol.70 número2Síndrome de DRESS inducido por fármacos antituberculososEventos adversos a medicamentos en pacientes hospitalizados: prevalencia, causas y factores de riesgo índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

  • Não possue artigos similaresSimilares em SciELO

Compartilhar


Revista alergia México

versão On-line ISSN 2448-9190

Resumo

MEDINA, Iris et al. Health related to quality life of patients with hereditary angioedema in Argentina. A multicenter study. Rev. alerg. Méx. [online]. 2023, vol.70, n.2, pp.64-71.  Epub 28-Ago-2023. ISSN 2448-9190.  https://doi.org/10.29262/ram.v70i2.1247.

Objective:

To describe health relaed quality of life in a cohort of stable adult outpatients with hereditary angioedema (HAE) with validated tools.

Methods:

An observational, cross-sectional, and descriptive study was performed, carried out in patients with hereditary angioedema, coming from the City of Buenos Aires and its provinces: Corrientes, Chubut, Entre Ríos and Santa Fe. The HAE-QoL and SF-12v2 health questionnaires were applied to assess the related quality of life. with health.

Results:

100 patients were included; median age: 41.5 years (range: 18-77); 65% were female, and 79% had type 1 HAE. Asymptomatic, mild, moderate and severe cases accounted for 6, 29, 38, and 27% of participants, respectively. Seventeen percent of patients were receiving long-term prophylaxis. Icatibant was the most frequent treatment for acute episodes. All health domains SF-12v2 scores were lower than expected in general population, excepting “vitality” and “physical functioning”. Total and all specific domains HAE-QoL scores were reduced. Differences between women and men and in every age-defined group were demonstrated for several specific domains.

Conclusions:

Health relaed to quality life was notably reduced in Argentinean patients with HAE, when implementing the HAE.QoL, and SF-12v2 questionnaries. The need for multidisciplinary strategies approaching this complex disease is highlighted.

Palavras-chave : Hereditary angioedema; Health-related quality of life; HAE-QoL; SF-12v2; Argentina.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )