Resumo

GUTIERREZ BAUTISTA, Deyanira et al. Long-term effects of COVID-19: a review of the literature. Acta méd. Grupo Ángeles [online]. 2021, vol.19, n.3, pp.421-428.  Epub 04-Abr-2022. ISSN 1870-7203.

COVID-19 has a wide spectrum of clinical manifestations, at least 55 long-term effects have been found including signs, symptoms and clinical parameters. The clinical stages of the disease are divided into an acute phase of COVID-19, post-acute phase, and post-COVID-19 syndrome. These phases are characterized by the development of signs and symptoms from the date of onset of symptoms and extend up to 4 weeks, between 4 and 12 weeks and beyond 12 weeks respectively. The prevalence varies from 35% to 94%, prevailing in most studies above 80%, with fatigue, cough and dyspnea being the most prevalent.The pathophysiological mechanisms that explain the development of symptoms include viral persistence, immune alterations and inflammation, expected sequel of critical illness, and specific pathophysiological alteration of acute disease in each system. The complete spectrum of post-COVID syndrome is still unknown, although many of its clinical components have been identified, information is still lacking to recognize the exact moment to determine its duration.

Palavras-chave : Post-acute COVID-19 syndrome; SARS-CoV-2 sequel; long COVID; persistent symptoms; post-COVID syndrome.

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