Introduction:

It has become essential to know the structural and cognitive changes that characterize the development of adults during aging and the biological roots of these changes to understand the transformations of the brain related to age and sex.

Objective:

The objective of the study was to determine the volumetry of the III ventricle according to age and sex, due to its wide use as a marker of cerebral atrophy as well as the elaboration of percentile tables that characterize this volumetry.

Methodology:

An analytical observational study was developed in 320 subjects with normal neurocognitive functions and neuropsychiatric examination, aged between 30 and 79 years, who underwent single-slice computed tomography of the skull. An image segmentation method was used based on the analysis of homogeneous textures and interpolation.

Results:

An increase in the volume of the third ventricle was obtained with respect to age. It was also demonstrated, the greater absolute volumes studied in men with respect to women. Based on these parameters, the mean values, confidence intervals, and percentiles of the lateral ventricles are described.

Conclusions:

The neuroimaging acquisition protocol implemented allowed us to obtain the volumetric parameters of the third ventricle in adults with normal global cognitive functions. These increased with the age. While sex had a significant effect, obtaining higher magnitudes in the male sex.

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