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Revista mexicana de neurociencia
versão On-line ISSN 2604-6180versão impressa ISSN 1665-5044
Resumo
HERNANDEZ-CORTES, Katherine S.; MESA-PUJALS, Adrián A.; SAGARO DEL CAMPO, Nelsa M. e PEDRON-ARQUIMEDES, Montoya. Volumetric of the lateral ventricles in computed tomography images in Cubans adults with normal cognitive functions. Rev. mex. neurocienc. [online]. 2023, vol.24, n.3, pp.61-70. Epub 12-Jun-2023. ISSN 2604-6180. https://doi.org/10.24875/rmn.22000058.
Introduction:
The use of morphometric methods based on neuroimaging to determine brain volumetric related to aging for clinical diagnosis has been largely restricted to high-resolution imaging techniques. Texture, as a method of image analysis, has shown promising results in the detection of visible and non-visible lesions, and that in computerized axial tomography studies they are scarce.
Objective:
The objective of the study was to evaluate the effect of normal aging on the volume of the lateral ventricles, estimated from single-slice computed tomography (CT) imaging techniques, using an automatic processing method of homogeneous texture indices.
Methodology:
An observational and analytical study was developed in 320 subjects with normal neurocognitive functions and neuropsychiatric examination, aged between 30 and 75 years and over, who underwent a single-slice Computed Axial Tomography of the skull. An image segmentation method based on homogeneity was used.
Results:
The analysis of variance showed that advancing age is associated with a proportional increase in the volume of the lateral ventricles.
Conclusions:
The morphometric method of the lateral ventricles developed from CT/homogeneity segmentation images, allows to quantify the cerebral volumetric changes associated with normal aging and can be used as a biomarker of cerebral atrophy.
Palavras-chave : Ventricular volumetric; Computed tomography; Normal cognitive functions.