Resumo

RIVERO ARIAS, Dulce María; RAMOS GOMEZ, Laura Isabel; CHAVEZ CARAZA, Karla L  e  BRIONES, Alejandra. Vulvar ulcer in a 15-year-old girl: can we recognize adverse drug reactions?. Bol. Med. Hosp. Infant. Mex. [online]. 2013, vol.70, n.3, pp.230-233. ISSN 1665-1146.

Background. Pediatricians consider vulvar ulcer as an uncommon pathology. However, clinicians specialized in the care of young girls and teenagers with vulvar pathology actually consider vulvar ulcer not to be an infrequent primary complaint. Case report. We report the case of a 15-year-old girl who presented fever and sore throat for which she was treated with trimethoprim-sulfamethoxazol. Two days after taking the drug she presented hyperpigmented patches with a bullous center that developed into an ulcer of ~4 cm in diameter. First considered infectious in origin, she received treatment with topical fluconazol and afterwards with amoxicillin clavulanate without any improvement. She was then assessed by a dermatologist, and the diagnosis of fixed drug eruption was established on the basis of the initial morphology of the lesion. She was treated with betamethasone and loratadine as well as topical 1% hydrocortisone. The lesions evolved to complete resolution. Conclusions. In pediatric practice, it is important for the pediatrician to consider not only infectious and venereal causes in teenage girls with vulvar ulcer, but also allergic drug reactions.

Palavras-chave : vulvar ulcer; fixed drug eruption; adverse drug reaction.

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