Serviços Personalizados
Journal
Artigo
Indicadores
- Citado por SciELO
- Acessos
Links relacionados
- Similares em SciELO
Compartilhar
Ginecología y obstetricia de México
versão impressa ISSN 0300-9041
Resumo
SANTIAGO SANABRIA, Leopoldo et al. Incidence of breast cancer at 5 years in women with premalignant lesions. Ginecol. obstet. Méx. [online]. 2023, vol.91, n.8, pp.549-561. Epub 17-Nov-2023. ISSN 0300-9041. https://doi.org/10.24245/gom.v91i8.8622.
OBJECTIVE:
To determine the cumulative incidence of breast cancer at five years of follow-up in patients with preinvasive or premalignant lesions of the mammary gland in a referral canter and to establish the associated risk factors.
MATERIALS AND METHODS:
Retrospective cohort study carried out in patients seen at Hospital Ángeles Lomas between 2012 and 2016 with a diagnosis, during their mastographic screening, of a precursor or pre-invasive lesion of breast cancer. Categorical variables are expressed in frequencies and percentages. The χ2 test was used for difference of proportions between groups.
RESULTS:
We obtained 3360 patients who attended the mastology service during the established time. We obtained 245 patients with premalignant lesions but 30 of them did not comply with the five-year follow-up and were lost within the stipulated surveillance period. This left 215 patients who met all the inclusion criteria. The overall cumulative incidence of invasive breast cancer was that at 5 years 14.9% of patients with premalignant lesions will have breast cancer. Lobular carcinoma in situ had the highest incidence or progression of invasive cancer, with 32.1% at 5 years, followed by mucocele-like lesions, ductal carcinoma in situ and intraductal papilloma with 23.1, 21.1 and 17.1%, respectively.
CONCLUSIONS:
Breast cancer remains a public health problem in Mexico and worldwide. Although more and better screening programmes are becoming available, this has brought with it other problems, such as premalignant or high-risk carcinogenic lesions, which have increased in incidence.
Palavras-chave : Cancer; Breast; Premalignant; Chemoprevention; Lesions; Preinvasive.