BACKGROUND:

DRESS syndrome is a severe, infrequent, and life-threatening toxicodermia.

CLINICAL CASE:

17-year-old patient, primitive, diagnosed with frontal lobe epilepsy, treated with 200 mg of carbamazepine every 12 hours. Two months after the beginning of the treatment, exanthema appeared on the face, trunk and abdomen, itching and fever of 38.5 ºC. She was treated with antihistamines and paracetamol, without improvement. She had generalized erythema, hyperkeratotic plaques on face and trunk, stomatitis and suppurative otitis media. She was admitted to the intensive care area with diagnosis of 30 weeks of pregnancy, with single live intrauterine fetus, without labor and dermatosis under study. Multiple discipline care began with the establishment of the diagnosis of DRESS syndrome. Obstetric ultrasound reported: altered fetal hemodynamics and laboratory studies with increased transaminases. It was decided to terminate the pregnancy by cesarean section, indicated by fetal distress and deterioration in the mother’s health conditions, without complications. It continued with the established treatment. Since the clinical evolution was favorable, she was discharged from the service.

CONCLUSIONS:

Although DRESS syndrome is rare, physicians should be careful in the care of pregnant patients with comorbidities and identify risk factors that may be related to the condition for timely diagnosis and treatment. When patients are properly treated, the syndrome will disappear spontaneously, with limited damage and uncomplicated recovery.

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