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Neumología y cirugía de tórax
versão impressa ISSN 0028-3746
Resumo
CARRETO-BINAGHI, Laura; GONZALEZ, Yolanda e GUZMAN-BELTRAN, Silvia. Pulmonary disease caused by nontuberculous mycobacteria: diagnosis, treatment and antimicrobial resistance mechanisms. Neumol. cir. torax [online]. 2021, vol.80, n.2, pp.141-153. Epub 01-Nov-2021. ISSN 0028-3746. https://doi.org/10.35366/100997.
Nontuberculous mycobacteria (NTM) are emerging pathogens that affect both immunocompromised and immunocompetent patients. The incidence and prevalence of NTM lung disease have been increasing significantly around the world. Therefore, the correct diagnosis and identification of the species responsible for the infection are essential. In addition, NTM natural resistance to the most commonly used antibiotics must be considered, in order to provide appropriate treatment to each patient. Finally, it is essential to identify possible multiple infections due to strains of M. tuberculosis and NTM, which are not routinely detected and are often difficult to distinguish, because the clinical symptoms cannot differentiate a single infection from a co-infection. This review is focused on all these aspects for the benefit of patients with NTM lung disease.
Palavras-chave : Nontuberculous mycobacteria; tuberculosis; bacterial resistance; antibiotics; coinfection.