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Neumología y cirugía de tórax
versão impressa ISSN 0028-3746
Resumo
SADA-OVALLE, Isabel; OCANA-GUZMAN, Ranferi e TORRE-BOUSCOULET, Luis. Biomass smoke, innate immunity and Mycobacterium tuberculosis. Neumol. cir. torax [online]. 2015, vol.74, n.2, pp.118-126. ISSN 0028-3746.
There is consistent epidemiological evidence linking independently, chronic smoke inhalation biofuel with the development of pulmonary tuberculosis. The pathophysiological mechanisms underlying this association are partially known. Smoke biofuel has different effects in the lung parenchyma and the innate immune system which, taken together, may increase susceptibility to various infections including Mycobacterium tuberculosis. In this review we describe the most important physicochemical characteristics of the particles in the smoke biofuel and how these affect some of the immunological mechanisms involved in the immune response against Mycobacterium tuberculosis.
Palavras-chave : Biofuels; lung diseases; tuberculosis.