SciELO - Scientific Electronic Library Online

 
vol.155 número3Análisis bibliométrico de las revistas médicas del Sistema de Clasificación de Revistas Mexicanas de Ciencia y TecnologíaDinámica mitocondrial en las enfermedades neurodegenerativas índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

  • Não possue artigos similaresSimilares em SciELO

Compartilhar


Gaceta médica de México

versão On-line ISSN 2696-1288versão impressa ISSN 0016-3813

Resumo

ORTIZ-BRIZUELA, Edgar et al. Enfermedad granulomatosa hepática. Gac. Méd. Méx [online]. 2019, vol.155, n.3, 10.  Epub 01-Jul-2021. ISSN 2696-1288.  https://doi.org/10.24875/gmm.18004327.

Granulomas are circumscribed lesions mainly composed of mononuclear cells that arise in response to poorly degradable antigenic stimuli. They are found in 2-15 % of liver biopsies and the meaning of their finding can range from an incidental phenomenon to the manifestation of a systemic disease of infectious, autoimmune or neoplastic origin. Clinical presentation usually points at the underlying pathology; however, the list of associated conditions is extensive, and differs based on patient epidemiological history and baseline characteristics. The most useful element for their study is a thorough medical history, with an emphasis on recent trips, exposures and consumption of drugs or raw or exotic foods. Detailed histopathological analysis may help identify the etiology. For example, the presence of epithelioid granulomas with caseous necrosis indicates tuberculosis and, its absence, sarcoidosis; eosinophil abundance can be associated with drug reactions or parasitic infections; and the presence of foreign bodies can be the cause of granulomatous liver disease (GLD). In this article, we describe the basic clinical-pathological aspects of GLD, and provide a brief summary of the most common etiologies, with an emphasis on the Latin-American region.

Palavras-chave : Granulomatous liver disease; Hepatic granuloma; Hepatic granulomatosis.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )