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Cirugía y cirujanos
versión On-line ISSN 2444-054Xversión impresa ISSN 0009-7411
Resumen
SAHIN, Mehmet H. et al. Predestinative role acidic cerebrospinal fluid on the destiny of central channel in spinal cord following subarachnoid hemorrhage: an experimental study. Cir. cir. [online]. 2023, vol.91, n.5, pp.627-632. Epub 30-Oct-2023. ISSN 2444-054X. https://doi.org/10.24875/ciru.22000578.
Objective:
Acidosis is the most dangerous complication in subarachnoid hemorrhage (SAH). This study aimed to investigate the effect of acidic cerebrospinal fluid on central canal structures after SAH.
Materials and methods:
Twenty-eight hybrid rabbits were studied. Blood and cerebrospinal fluid pH values were recorded before/during/after the experimental procedures. The structures related to the central canals at the level of C5 of the cervical spinal cord were then examined histopathologically. The relationship between pH values of ependymal cells and degenerated epithelial cell densities was statistically analyzed.
Results:
Mean blood pH values and degenerated ependymal cell density (n/mm2) were as follows: 7.351 ± 0.033/23 ± 7 in control, 7.322 ± 0.059/78 ± 13 in SHAM, and 7.261 ± 0.048/254 ± 62 in study animals. Gross examinations revealed swelling, edema, pia-arachnoid adhesions, ventral canal dilatation, arachnoiditis, central canal hemorrhage, occlusions, and dilatation in the spinal cord.
Conclusion:
Cerebrospinal fluid acidosis-induced central channel pathologies should be considered an important complication of SAH following SAH.
Palabras llave : Subarachnoid hemorrhage; Ependymal cell desquamation; Acidosis; Cerebrospinal fluid.