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Cirugía y cirujanos
versión On-line ISSN 2444-054Xversión impresa ISSN 0009-7411
Resumen
XU, Ziyang et al. Prognostic analysis and outcome of hilar cholangiocarcinoma after radical resection: a retrospective study. Cir. cir. [online]. 2023, vol.91, n.4, pp.486-493. Epub 30-Oct-2023. ISSN 2444-054X. https://doi.org/10.24875/ciru.22000589.
Objectives:
The predictive factors affecting the survival of hilar cholangiocarcinoma (HC) are ambiguous. This study aimed to identify the predictors and recurrence patterns of HC.
Methods:
A retrospective analysis of the clinicopathological findings of 126 patients with HC from 2009 to 2019 was performed.
Results:
The proportion of Bismuth I and II HC in the recurrence group was higher than that in the non-recurrence group (p < 0.01). The recurrence group had poorer tumor differentiation, a more advanced N stage, and a higher incidence of perineural invasion compared with the non-recurrence group. N stage and tumor differentiation were independently associated with disease-free and overall survival of patients (p < 0.01). Bile duct resection (BDR) combined with hepatectomy was more favorable to disease-free and overall survivals than BDR alone in Bismuth I and II HC, although p values were marginal (p = 0.072 and p = 0.045). A higher proportion of patients in the non-recurrence group underwent BDR combined with hepatectomy than that in the recurrence group (p < 0.01).
Conclusions:
N stage and tumor differentiation are the two independent predictors of patient survival. BDR combined with hepatectomy is recommended for patients with Bismuth I and II hilar cholangiocarcinoma.
Palabras llave : Hilar cholangiocarcinoma; Bismuth classification; Survival; Bile duct resection; Hepatectomy.