Resumen

PEREZ HERNANDEZ, Raymundo Alejandro et al. In vitro effect on the inhibition of the process of nucleation in renal lithiasis, ability to capture radical free, antimicrobial and toxic of methanol extract of Berberis trifoliate. Rev. mex. cienc. farm [online]. 2015, vol.46, n.1, pp.70-76. ISSN 1870-0195.

In vitro antiurolithic, antimicrobial and free radicals scavenger activities, toxicity, and phytochemical composition of methanolic extract of aerial parts of Berberis trifoliata was evaluated. The studied extract inhibits up to a 93 ± 0.01 % the nucleation of crystals of calcium oxalate at a concentration of 1000 μg/mL and have free radical scavenging activity with a CE50 = 12.84 μg/mL. The extract did not exhibit antimicrobial activity against isolated clinical bacteria that causes urinary infections. In terms of toxicity against Artemia salina, the extract showed a medium lethal concentration value of 925 μ g/mL. It has a diversity of compounds and functional groups like carbohydrates, coumarins, double bonds, flavonoids, carboxyl group, sesquiterpenlactones, alkaloids and tannins.

Palabras llave : Berberis trifoliata; antiurolithic; antimicrobial; antiradical; toxicity.

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