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Ginecología y obstetricia de México
versión impresa ISSN 0300-9041
Resumen
CARRANZA-LIRA, Sebastián; RODRIGUEZ-ACOSTA, Grecia Carmín y HERNANDEZ-ANGELES, Luis Claudio Erick. Difference in neutrophil/lymphocyte index between patients with polycystic ovarian syndrome and healthy women. Ginecol. obstet. Méx. [online]. 2019, vol.87, n.12, pp.802-806. Epub 30-Ago-2021. ISSN 0300-9041. https://doi.org/10.24245/gom.v87i12.3439.
OBJECTIVE:
To determine the difference in the neutrophil/lymphocyte index between PCOS patients and healthy women.
MATERIALS AND METHODS:
Descriptive, retrospective, cross-sectional, comparative study. Women with PCOS were studied in which glucose, lipids, testosterone, androstenedione and dehydroepiandrosterone sulfate were measured, also a blood count was performed, and the neutrophil/lymphocyte index was calculated. The results were compared with healthy controls studied for infertility. For statistical analysis, Mann-Whitney U and Spearman correlation analysis were used.
RESULTS:
112 patients divided as follows were studied: group I with PCOS (n = 63) and group II healthy women (n = 49). The median age was for group I: 27 (14-39) and group II: 28 (16-41) years without statistically significant difference between them, also there were not between the groups in the concentrations of glucose, cholesterol and triglycerides. The neutrophil/lymphocyte index was significantly higher in the group with PCOS, 1.9 (0.9-7.4) vs 1.4 (0.8-3.9), p < 0.000, respectively.
CONCLUSION:
PCOS is associated with a chronic inflammatory process that may confer greater cardiovascular risk.
Palabras llave : Neutrophil/lymphocyte index; Glucose; Lipids; Cardiovascular diseases; Risk factors; Androstenedione.