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Ginecología y obstetricia de México
versión impresa ISSN 0300-9041
Resumen
MELENDEZ-GONZALEZ, Claudia Victoria; SALDANA-SOLORZANO, César Francisco; MACHORRO-GARCIA, Erick Genaro y GONZALEZ-HABIB, Roberto. Correlation between risk malignancy index Jacobs II and anatomopathological result in ovary tumors. Ginecol. obstet. Méx. [online]. 2019, vol.87, n.5, pp.277-287. Epub 30-Jun-2021. ISSN 0300-9041. https://doi.org/10.24245/gom.v87i5.2680.
OBJECTIVE:
To determine the correlation between the risk of malignancy index Jacobs II and anatomopathological result in ovarian tumors.
MATERIALS AND METHODS:
Observational, retrospective, prospective, analytical and transversal study of patients with a diagnosis of ovarian tumor with tumor marker of Ca 125 and the result of pathology admitted to the Christus Muguerza Conchita Hospital in Nuevo León during a 2-year period (2016-2018). Risk of malignancy index Jacobs II was calculated: IRM = U x M x Ca 125. Two groups were divided according to the results of histopathology (benign and malignant). For variables of central tendency, were compared with Student's t-test adjusted to two-tailed normality (P <0.05). For categorical sampling, compared with the 2-tailed Fisher's test to describe the differences between the groups or distribution c2 (P <0.05). The sample was studied to observe risk / benefit factors (AUROC) as well as determination of the odds ratio, relative risk, sensitivity, specificity and creation of the logistic regression model of the indicators of interest.
RESULTS:
It was found that patients with a Jacobs II malignancy index higher than 155.22 (AUROC 0.95) were more likely to have a malignant lesion due to pathology with 88% sensitivity and 91% specificity.
CONCLUSION:
There is a correlation between the risk index for malignancy of Jacobs II and the anatomopathological result in ovarian tumors.
Palabras llave : Ovarian tumor; Tumor marker; Ovarian Neoplasms; Biomarkers, Tumor.