BACKGROUND:

Elevated levels of gamma-glutamyl transpeptidase (GGT) have been associated with the risk of ischemic heart disease, diabetes mellitus and stroke.

OBJECTIVE:

To determine, by means of standardized statistical methods, that the serum elevation of GGT is an early predictor of ischemic stroke in the Mexican population.

MATERIAL AND METHOD:

A case-control study was conducted with measurement of serum GGT in patients with chronic-degenerative diseases without cardiovascular events and chronic patients with an adverse cardiovascular event, in this case, an ischemic stroke, done from May 2016 to June 2017.

RESULTS:

A total of 74 patients were analyzed; patients with ischemic stroke presented, on average, 17.81 U/L of GGT more than controls adjusted for age, with a statistically significant difference (p = 0.038, 95%CI 1.04- 34.57).

CONCLUSIONS:

GGT levels correlated directly with cardiovascular risk, which is of great importance, since it has been shown that serum levels can be reduced with measures such as diet and exercise, so that a broad panorama opens up for further studies that can reaffirm the validity of this study and do others with a preventive approach.

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