Servicios Personalizados
Revista
Articulo
Indicadores
- Citado por SciELO
- Accesos
Links relacionados
- Similares en SciELO
Compartir
Revista de la Facultad de Medicina (México)
versión On-line ISSN 2448-4865versión impresa ISSN 0026-1742
Resumen
GARCIA DAVILA, Rocío Elizabeth et al. Usefulness of Positron Emission Tomography/Computed Tomography (PET/CT) in Patients Diagnosed with Medulloblastoma. Rev. Fac. Med. (Méx.) [online]. 2020, vol.63, n.1, pp.34-41. Epub 05-Mar-2021. ISSN 2448-4865. https://doi.org/10.22201/fm.24484865e.2020.63.1.06.
PET/CT (positron emission tomography/computed tomography, for its acronym in English) is a unique imaging method that provides in vivo evidence of both biochemical and physiological activities of the brain, spinal cord and tumors that involve these structures. Medulloblastoma is the most common malignant tumor of the central nervous system (CNS) in pediatric patients, so PET/CT plays an important role as it provides information on the grade and extent of the tumor, as well as to determine the appropriate site for the biopsy, assessing the response to the treatment and the patient’s prognosis.
There are different radiopharmaceuticals for the evaluation of central nervous system tumors, but 18F FDG (Fluor-2-fluoro-2-desoxy-D-glucose) and 68Ga-DOTA-NOC (68Ga-DOTA0-1NaI3-octreotide) have been studied to help us evaluate and follow up patients diagnosed with medulloblastoma. Medulloblastoma has an overexpression of glucose transporters, mainly type 1, and an overexpression of predominantly type 2 somatostatin receptors, which allows a high affinity for these radiopharmaceuticals.
Palabras llave : Medulloblastoma; positron emission tomography; PET/C; 18F-FDG; 68Ga-DOTA-NOC; brain tumor.