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Revista alergia México
versión On-line ISSN 2448-9190
Resumen
PIMENTA E SILVA, Luiz Marcelo et al. Hereditary bradykinin angioedema. Case report. Rev. alerg. Méx. [online]. 2022, vol.69, n.3, pp.138-141. Epub 19-Mayo-2023. ISSN 2448-9190. https://doi.org/10.29262/ram.v69i3.1057.
Introduction:
Hereditary angioedema is an autosomal dominant genetic disease, associated with increased levels of bradykinin. It is classified into 3 types according to the C1-INH enzyme. The diagnosis is clinical and laboratory. Its treatment is divided into short- and long-term and crisis prophylaxis.
Case report:
40-year-old female patient who came to the emergency service for labial edema without resolution with corticosteroids. The tests for IgE, C4 and C1 esterase inhibitors had a low result. She currently uses danazol prophylactically and fresh frozen plasma in crises.
Conclusion:
Since it is a disease that considerably affects the quality of life, hereditary angioedema must be diagnosed and an effective treatment plan made to prevent or reduce its complications.
Palabras llave : Hereditary Angioedema; Bradykinin; C1 inhibitor; Serping 1 gene.