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Medicina crítica (Colegio Mexicano de Medicina Crítica)
versión impresa ISSN 2448-8909
Resumen
TRUJILLO RAMIREZ, Nancy et al. Lactate/albumin index as a sepsis mortality predictor and septic shock. Med. crít. (Col. Mex. Med. Crít.) [online]. 2018, vol.32, n.3, pp.136-140. Epub 27-Mar-2020. ISSN 2448-8909.
Introduction:
The correlation between lactate and serum albumin seems to be a novel alternative for estimating mortality. These are serum markers that are routinely used, which means that there is no increase in the expenditure of resources.
General objective:
To report the relationship of lactate/albumin index in patients with sepsis and septic shock with mortality after intensive care.
Material and methods:
A historical cohort study was performed, where a sample of 30 patients was calculated from which the data were collected in the instrument, taken from the clinical file.
Results:
The lactate/albumin index was a good prognostic marker for the determination of mortality in sepsis and in septic shock with statistical significance p < 0.001. It fulfills the hypothesis by showing that a lactate/albumin index greater than 1.7 was correlated with a Mortality greater than 40% in sepsis. We found a strong relationship with lactate clearance in six hours with satisfactory results as a predictor of mortality. The lactate / albumin index was not related to the development of multiple organ dysfunction.
Conclusions:
The lactate/albumin index greater than 1.7 is related to a mortality greater than 40% in patients with sepsis. There is no relationship of the lactate / albumin index with the development of DOM. There is a positive correlation of the index with the predictive scales of SAPS, APACHEII and SOFA. The area under the ROC curve was higher for the lactate/albumin index and lactate clearance at 6 hours, as compared to the prognostic scales.
Palabras llave : Lactate and albumin association; mortality; septic shock; sepsis; index.